Every day the human arm performs hundreds of tasks, ranging from simple to relatively complex. For a person who wears a prostheses or has other problems with their arms, each one of these movements can be challenging. This work estimates the forces and moments occurring in the joints of normal children and prostheses users. This …
Tag Archive: HealthSciences
Mar
12
Les accidents de la route impliquant des enfants pietons Analyse spatiale des risques potentiels et des risques percus pour une meilleure prevention
Un des points forts de cette these provient de la combinaison de deux approches methodologiques. La premiere, provenant de la science de linformation geographique, passe par lintegration de sources de donnees diverses decrivant lenvironnement urbain autour des ecoles dans un systeme dinformation geographique. La seconde phase de notre projet, sapparentant aux enquetes psychometriques avec questionnaire, …
Mar
11
Characterization and evaluation of surface modified superparamagnetic iron oxide nanoparticles for uptake into human prostate carcinoma cells
Magnetic nanoparticles MNPs) were synthesized from Fe2＋ and Fe3＋ by the co-precipitation method. Two nanoparticle surface coatings gum arabic and sodium citrate) provided additional functionalization and cell selectivity. The incorporation of surface modifiers to the synthesized nanoparticles generated three nanoparticle systems from which the research was based. The physical and chemical properties were determined with …
Mar
10
Quantitative perfusion-sensitive MRI phantoms
Perfusion-sensitive MR methods are increasingly utilized in preclinical and clinical MR research studies with the promise of providing quantitative estimates of parameters that describe in vivo microvasculature. One of these techniques, dynamic contrast enhanced DCE) MRI, has found particularly common use in oncology for the detection, staging, and monitoring of highly vascularized tumors. DCE-MRI has …
Mar
09
Dynamic cardiovascular magnetic resonance imaging for improved assessment of ischemic heart disease
Magnetic resonance imaging MRI) is one of the most powerful non-invasive imaging modalities whose strengths include flexible tissue contrast, sensitivity to flow, and the lack of any harmful radiation. Ischemic heart disease IHD) is a leading cause of death in the western world, and as such, MR approaches for the assessment of IHD have gained …
Mar
09
Spatiotemporal dynamics of low frequency fluctuations in BOLD fMRI
Traditional fMRI utilizes blood oxygenation level dependent BOLD) contrast to map brain activity. BOLD signal is sensitive to the hemodynamic changes associated with brain activity, and gives an indirect measure of brain activity. Low frequency fluctuations LFFs) have been observed in the BOLD signal even in the absence of any anesthetic agent, and the correlations …
Mar
09
Lyophilized vaccine preparations containing aluminum salt adjuvants: Preparation, immunogenicity, and stability
Vaccine products containing recombinant antigens must include an adjuvant to aid in the potentiation of the immune response. The only adjuvants currently appearing in FDA-approved products are the aluminum-salt adjuvants aluminum hydroxide and aluminum phosphate. A lyophilized vaccine product would be highly beneficial due to the improved stability of dried formulations. However, there is some …
Mar
08
Active staining for in vivo magnetic resonance microscopy of the mouse brain
Mice have become the preferred model system for studying brain function and disease. With the powerful genetic tools available, mouse models can be created to study the underlying molecular basis of neurobiology in vivo. Just as magnetic resonance imaging is the dominant tool for evaluating the human brain, high-resolution MRI—magnetic resonance microscopy MRM)—is a useful …
Mar
08
Validation of EIT using Simultaneous Dynamic CT images
Electrical impedance tomography (EIT) estimates a cross-sectional conductivity image of a body from surface electrical measurements. One promising application of EIT is for monitoring lung ventilation to help optimize management of intensive care patients. To test the applicability of EIT for this application, it is important to validate EIT images to understanding of the magnitude …
Mar
06
Detection of emerging pandemic influenza strains by surface plasmon resonance and electrically-active magnetic nanoparticle-based biosensor
Rapid detection technologies including surface plasmon resonance (SPR) and nanomaterial based biosensors are emerging as sensitive, specific, and rapid diagnostic tools for the detection of highly pathogenic viruses. This research demonstrates the novel application of SPR and nano-biosensors for Influenza A virus (FLUAV) detection, utilizing specificity of binding between FLUAV hemagglutinin (HA) and host sialic …